Family-Based Screening of Thalassemia: A Study of Relatives of Diagnosed Children

Abstract

Thalassemia is a dangerous inherited blood disorder that poses a significant health risk, particularly in regions where the gene is prevalent. This study screened 320 members of families of children diagnosed with thalassemia to identify carriers. Findings revealed that 25.6% of participants were carriers, indicating a substantial genetic risk. This highlights the importance of cascade screening and structured genetic counseling to prevent transmission in future generations. Disseminating knowledge and supporting families can reduce new cases and empower informed reproductive decisions.